Who has the ADAM9 gene?

ADAM9 expression is detected in multiple cell types, including monocytes [12], macrophages [13], neutrophils [14], keratinocytes [15], and fibroblasts [16]; and in multiple tissues, including lung [17], colon [18], kidney [19], vascular smooth muscle [20,21], nervous system [1,22], reproductive system [23], and …

What is the function of a Disintegrin?

Disintegrins are a family of small proteins (45–84 amino acids in length) from viper venoms that function as potent inhibitors of both platelet aggregation and integrin-dependent cell adhesion.

What is Disintegrin domain?

Description. Disintegrins are a family of small proteins from viper venoms that function as potent inhibitors of both platelet aggregation and integrin-dependent cell adhesion. [1, 2] .

What is Echistatin?

Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1.

How are MMPs inactivated?

Oxidants generated by leukocytes or other cells can both activate (via oxidation of the prodomain thiol followed by autolytic cleavage) and subsequently inactivate MMPs (via modification of amino acids critical for catalytic activity), providing a mechanism to control quantum bursts of proteolytic activity.

What is ADAM9?

Disintegrin and metalloproteinase domain-containing protein 9 is an enzyme that in humans is encoded by the ADAM9 gene. This gene encodes a member of the ADAM ( a disintegrin and metalloprotease domain) family.

How long did Adam live in the Bible?

3 When Adam had lived 130 years, he had a son in his own likeness, in his own image; and he named him Seth. 4 After Seth was born, Adam lived 800 years and had other sons and daughters. 5 Altogether, Adam lived a total of 930 years, and then he died.

What does Adam stand for?

This gene encodes a member of the ADAM ( a disintegrin and metalloprotease domain) family.

What is the story of Adam’s family line?

This is the written account of Adam’s family line. When God created mankind, he made them in the likeness of God. 2 He created them male and female and blessed them. And he named them “Mankind” when they were created.