Miscellaneous

What is the first line treatment for onychomycosis?

What is the first line treatment for onychomycosis?

Itraconazole is first line of treatment for dermatophyte onychomycosis (level A) Fluconazole considered as second line if itraconazole and terbinafine contraindicated or not tolerated (level B)

How many types of onychomycosis are there?

Four types of onychomycosis are recognized based on the site and pattern of fungal invasion. Dermatophyte fungi are the predominant pathogens, but yeasts (especially Candida albicans) and nondermatophyte molds may also be implicated. Accurate diagnosis requires direct microscopy and fungal culture.

Is it possible to cure onychomycosis?

To successfully cure toenail onychomycosis requires long treatment duration that may extend to a full year. Even then, complete cure, defined as clinical cure (implying nail clearing) plus mycological cure (both negative microscopy and dermatophyte culture), is often unattainable.

Does ciclopirox treat onychomycosis?

Results: Data from the pivotal US trials have demonstrated that ciclopirox nail lacquer 8% topical solution is significantly more effective than placebo in the treatment of onychomycosis caused by Trichophyton rubrum, and of mild to moderate toe onychomycosis without lunula involvement.

What is the most common cause of onychomycosis?

Dermatophytes are by far the most common cause of onychomycosis. Two major pathogens are responsible for approximately 90% of all onychomycosis cases. Trichophyton rubrum accounts for 70% and Trichophyton mentagrophytes accounts for 20% of all cases.

Is onychomycosis serious?

It is uncommon for an infected nail to cause severe pain or permanent disfigurement, but this does occur in some cases. If left untreated, fungal nail infections can cause difficulties with walking, exercising or manual tasks such as typing. The main symptoms of onychomycosis include the nail becoming: Brittle.

Where does onychomycosis start?

Most types of onychomycosis have the same signs of infection: the infected nail usually becomes thick and discoloured. This process generally starts at the tip of the nail and progresses downwards towards the root. As the infection progresses, the affected nail can become itchy and/or slightly painful.