What is the drug of choice for chemotherapy and radiation induced vomiting?
The most commonly used treatment for chemotherapy-induced nausea and vomiting from moderately and highly emetogenic regimens is a combination of serotonin (5-HT3) receptor antagonists, a steroid (dexamethasone), and a neurokinin-1 (NK1) receptor antagonist (aprepitant).
What is the best antiemetic for chemotherapy?
Low emetogenic chemotherapy Within the first 24 hours, all guidelines recommend dexamethasone as the antiemetic of choice, while dopamine receptor antagonist or 5-HT3 receptor antagonist have been recommended as alternatives to dexamethasone by MASCC/ESMO and NCCN guidelines.
What drug should be administered to a client on chemotherapy to prevent nausea and vomiting?
However, if the chemotherapy is likely to cause nausea and vomiting, your doctor may prescribe one or more of the following common anti-nausea medications: Aprepitant (Emend®) Dolasetron (Anzemet®) Granisetron (Kytril®)
What helps with nausea from radiation therapy?
Cancer: Home Treatment for Nausea or Vomiting
- Take any antinausea medicines as your doctor recommends.
- Make sure you drink enough liquids so you don’t get dehydrated.
- Make sure to eat enough food.
- Suck on peppermint candy, or chew a stick of peppermint gum.
- Try ginger, such as candied ginger or ginger tea.
Which drug would be most beneficial to treat nausea and vomiting caused by chemotherapy?
Benzodiazepines. These agents are anxiolytics that are used in patients receiving chemotherapy. Benzodiazepines are appropriate adjunct therapies to decrease treatment-related anxiety, and they are the preferred agents to treat and prevent anticipatory nausea and vomiting.
What helps with nausea and vomiting during chemo?
The following are suggestions to minimize your discomfort:
- Avoid your favorite food.
- Talk to your doctor about nausea medications.
- Avoid strong smells.
- Avoid warm foods.
- Eat every 2-3 hours.
- Eat what you want to eat.
- Drink liquids in-between meals/snacks.
- Use ginger and peppermint.
Which antiemetic is especially helpful in treating nausea and vomiting resulting from chemotherapy?
The NCCN guidelines recommend the use of benzodiazepines to treat ANV. For radiation-induced nausea and vomiting, 5-HT3 receptor antagonists are the preferred class of antiemetic.
Does radiation therapy cause nausea and vomiting?
Radiation therapy may also cause nausea and vomiting. The part of the body where the radiation therapy is given. Radiation therapy to the gastrointestinal tract, liver, or brain, or whole body is likely to cause nausea and vomiting.
How fast does Zofran work?
How quickly does Zofran (ondansetron) work? Zofran (ondansetron) should work pretty quickly. Many people report relief within about 30 minutes and it reaches maximum blood concentrations in about 2 hours. The effects of Zofran (ondansetron) can last anywhere between 8 to 12 hours.
How does dexamethasone work as an antiemetic?
The mechanism for the antiemetic effect of dexamethasone has been incompletely understood but it is thought to be caused by the inhibition of prostaglandin synthesis, by showing anti-inflammatory efficacy and by causing a decrease in the release of endogenous opiates17,18.