What diseases do hematopoietic stem cells treat?
There are over 2100 clinical studies in progress concerning hematopoietic stem cell therapies. All of them are using hematopoietic stem cells to treat various diseases like: cancers, leukemia, lymphoma, cardiac failure, neural disorders, auto-immune diseases, immunodeficiency, metabolic or genetic disorders.
Is bone marrow transplant done in Africa?
In addition to Tanzania, African countries, which currently perform bone marrow transplants, are South Africa, Tunisia, Egypt, Comoro and Nigeria.
How is sickle cell treated in Africa?
Currently, transplantation of haematopoietic stem cells (HSCs) is the only accepted curative treatment for SCD.
Why will hematopoietic stem cells used?
Hematopoietic stem cell transplantation (HSCT) involves the intravenous infusion of hematopoietic stem cells in order to reestablish blood cell production in patients whose bone marrow or immune system is damaged or defective.
Can stem cell transplant be done in Nigeria?
Late in 2011, Nigeria became only the third African country to undertake a stem cell transplant, after South Africa and Tanzania.
How much is stem cell transplant in Nigeria?
twenty-five million Naira
BMT IS EXPENSIVE: Most people travel abroad for the procedure and total cost of the procedure, air travel, food and board for about 6 months for patient and care giver add up to about a whopping N25m (twenty-five million Naira) per patient!
Why is sickle cell disease more common in Africa?
The disease is most common in sub-Saharan Africa, where as many as 45% of people are carriers. It has become so widespread there because being a carrier offers a survival advantage against malaria.
Why is sickle cell beneficial in Africa?
Although the sickle mutation at one allele of the beta-globin gene (heterozygosity) confers a survival advantage in malaria endemic areas, especially for children, inheritance of the mutation at both alleles (HbSS) predisposes individuals to severe malaria and increased malaria mortality, as well as increased mortality …
What is hematopoietic stem cell treatment?
Hematopoietic stem cell transplantation (HSCT) is a treatment for some types of cancer and other diseases. Stem cells can come from blood or bone marrow. Stem cells are non-differentiated cells. They can develop into various “specialist” cells in the body.
What are haematopoietic stem cells?
Hematopoietic stem cells (HSCs) are the stem cells that repopulate the blood and immune system within humans, via a process known as haematopoiesis.
What are hematopoietic stem cells (HSC)?
Hematopoietic stem cells (HSCs) are the stem cells that repopulate the blood and immune system within humans, via a process known as haematopoiesis. For this reason, hematopoietic stem cell transplantation, better known as HSCT, can be a promising treatment approach for a wide range of conditions.
How many hematopoietic stem cell transplants have been performed?
The first successful hematopoietic stem cell transplantation was performed in 1984. To date, approximately 1,200 transplants have been reported. Given the high prevalence of this disorder in Africa, and its emergence in the developed world through immigration, this number is relatively small.
What diseases can be treated with hematopoietic stem cells?
Diseases Treatable with Hematopoietic Stem Cells in the Future 1 Alzheimer’s 2 Dementia 3 Huntington’s Disease 4 Cerebral Palsy 5 Down’s Syndrome