What causes high alkaline phosphatase in child?

ALP levels are typically elevated during childhood and puberty due to bone growth and development. Between the ages of 15 to 50 years, ALP levels are slightly higher in males than females. ALP levels then rise again in old age.

What happens if alkaline phosphatase is too high?

Higher-than-normal levels of ALP in your blood may indicate a health concern with your liver or gallbladder. This could include a blockage in your bile ducts, gallstones, cirrhosis, liver cancer, and some forms of hepatitis.

Can growth spurts cause high alkaline phosphatase?

Normal Results Adults have lower levels of ALP than children. Bones that are still growing produce higher levels of ALP. During some growth spurts, levels can be as high as 500 IU/L or 835 µKat/L. For this reason, the test is usually not done in children, and abnormal results refer to adults.

Why the normal value of child alkaline phosphatase is higher than adults?

For men and women older than age 18, an ALP level between 44 and 147 U/L is considered normal. The normal range for children is higher than that for adults, especially for infants and teens because their bones are growing rapidly.

Can puberty cause high alkaline phosphatase?

Because ALP is a marker of osteoblastic activity, its level is higher in growing children than in fully grown adults, and the highest ALP level is detected during the rapid growth phases of childhood such as infancy and puberty18).

Is alkaline phosphatase lower after puberty?

There was no difference in ALP levels between boys and girls until puberty. However, higher ALP levels were noted at 10-11 years in girls (p=0.02) and at 12-13, 14-15, 16-17 years in boys (p<0.001). ALP levels start to decline after age 12 and 14 in girls and boys, respectively.

Can vitamin D deficiency cause elevated alkaline phosphatase?

Elevated serum alkaline phosphatase (ALP) level is an essential marker for the diagnosis of vitamin D deficiency (1). Some cases of vitamin D deficiency are diagnosed accidentally on the basis of elevated ALP levels.

What is the normal alkaline phosphatase in children?

The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and gender. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women.

What is alkaline phosphatase for kids?

What is it? An alkaline phosphatase (ALP) test measures the amount of the enzyme ALP in your child’s blood. ALP is made mostly in the liver and in bone. But some of it is made in the intestines and kidneys.

What foods increase alkaline phosphatase?

Foods rich in zinc, phosphorus and vitamin B12 help increase alkaline phosphatase levels in your body. All of these nutrients can be found in beef, poultry and seafood. Oils, such as coconut and corn, may also raise your alkaline phosphatase.

Can too much vitamin D cause elevated liver enzymes?

Neither normal nor excessively high intakes of vitamin D are associated with liver injury or liver test abnormalities.