What are the side effects of intravesical Mitomycin?

What are the side effects of intravesical Mitomycin?

soreness, pain or discomfort in the bladder. a skin rash, itching, feeling short of breath, wheezing, fever, shivers, or feeling dizzy or unwell in any way (allergic reaction).

Is cystitis a side effect of chemotherapy?

Specifically, some chemotherapy drugs, treatments delivered into your bladder and/or radiation to the pelvis can cause an irritation to the lining of your bladder, called cystitis. Cystitis can be severe, causing your bladder to bleed and increasing your risk of infection.

Does Mitomycin affect your immune system?

Mitomycin can also weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness).

Does mitomycin make you tired?

Common side effects of Mutamycin (mitomycin) include nausea and vomiting (may be severe), stomach/abdominal pain, loss of appetite, headache, blurred vision, drowsiness, dizziness, or weakness.

How long do Mitomycin-C side effects last?

Most patients do not have major problems, but you may have some side effects. These can start a few hours after treatment and may last 1 to 2 days. These side effects usually last less than 2 days. If you feel any burning or pain, have to urinate often, or see blood in the toilet bowl, drink about 4 glasses of water.

Which anticancer drugs cause hemorrhagic cystitis?

The most common pharmacologic causes of hemorrhagic cystitis are the oxazaphosphorine-alkylating agents cyclophosphamide and ifosfamide.

Does Mitomycin make you tired?

Does Mitomycin cause fatigue?

Feeling very tired is a common side effect. Fatigue is often worst toward the end of treatment and for a few months after the treatment has finished. You may lose your appetite during the treatment. Try to eat in small quantities and have frequent meals.

Do you lose your hair with Mitomycin?

Mitomycin sometimes causes a temporary loss of hair. After treatment has ended, normal hair growth should return. After you stop using this medicine, it may still produce some side effects that need attention.

What are the possible side effects of intravesical chemotherapy with mitomycin C?

The nature and severity of side effects accompanying intravesical chemotherapy with mitomycin C were studied in 29 patients. No patient experienced systemic toxicity. Local side effects developed in 7 patients (24 per cent), and consisted of moderate cystitis in 3 and drug-related palmar desquamation, with or without generalized rash, in 4.

What are the signs and symptoms of mitomycin C cystitis?

Mitomycin C cystitis can occur with just a single dose in mitomycin C naïve patients. Symptoms can range from mild irritative voiding symtpoms which are self-limited to severe, debilitating dysuria and pain. It can be refractory to behavioral therapies, and treatment with anticholinergics and alpha blockers.

Can mitomycin C be used to treat bladder cancer?

Our algorithm has been used successfully to treat this condition in several patients. Mitomycin C is recommended as a form of intravesical chemotherapy as either a single perioperative dose or as part of induction therapy for patients with low risk Ta bladder cancer [ 2, 3 ].

Do the side effects of mitomycin go away?

Some side effects of mitomycin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.