Does memantine improve cognition in dementia?

In our study, there is a significant improvement in cognition in memantine group assessed by MMSE score compared with the placebo.

Does memantine slow down dementia?

Medications containing the drug memantine are supposed to help people who have Alzheimer’s disease remember things and better manage their daily tasks. Studies show that memantine can somewhat delay the worsening of cognitive (mental) performance. Other abilities important in daily life may also last longer.

Can you use memantine for vascular dementia?

Alzheimer’s disease medicines, such as donepezil (Aricept), galantamine (Reminyl), rivastigmine (Exelon) or memantine are not used to treat vascular dementia, but may be used in people who have a combination of vascular dementia and Alzheimer’s disease.

Does Namenda help with agitation?

Findings from a recent study presented at the annual meeting of the American Association of Geriatric Psychiatry suggest that memantine (Namenda) therapy may significantly reduce agitation or aggression as well as improve appetite in patients with moderate-to-severe AD who are already receiving stable doses of …

How long is memantine effective?

Memantine is well absorbed from the gastrointestinal tract after oral administration, and its absorption is unaffected by food (Forest Laboratories 2003). It reaches a maximum plasma concentration (Cmax) after a single dose in 3–7 hours, and it has a plasma half-life of about 60–80 hours.

How do you increase the dose of Namenda?

The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice daily), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice daily). The minimum recommended interval between dose increases is one week. The dosage shown to be effective in controlled clinical trials is 20 mg/day. NAMENDA can be taken with or without food.

What is the generic name for Namenda?

Namenda Generic name: memantine (meh MAN teen) Brand name: Namenda, Namenda XR Drug class: Miscellaneous central nervous system agents

How does Namenda treat Alzheimer’s disease?

Namenda (memantine) reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer’s disease. Namenda is used to treat moderate to severe dementia of the Alzheimer’s type.

What are the side effects of Namenda?

Namenda can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. You should not use Namenda if you are allergic to memantine. To make sure Namenda is safe for you, tell your doctor if you have: a bladder or kidney infection.