Can meropenem cause death?
Deaths in 5 patients were assessed as possibly related to meropenem; 36 (1.2%) patients had meropenem discontinued because of adverse events. Many patients in these trials were severely ill and had multiple background diseases, physiological impairments and were receiving multiple other drug therapies.
How many days should meropenem be given?
Clinical practice guidelines recommend meropenem for 4 to 7 days for severe or high-risk community-acquired infections or complicated health-care associated infections. 20 mg/kg/dose IV every 8 hours (Max: 1 g/dose).
Where is meropenem injected?
Meropenem injection comes as a powder to be mixed with liquid and injected intravenously (into a vein). It is usually given every 8 hours.
Does meropenem affect kidney?
Importantly, meropenem-related seizures were rare (0.1%), even in patients with renal impairment. In summary, meropenem has an excellent safety profile and is therefore suitable for use in elderly and/or renally impaired patients.
Is meropenem safe to use?
Meropenem may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and requires immediate medical attention.
Why Meropenem injection is used?
Meropenem injection is used to treat infections caused by bacteria. It works by killing the bacteria or preventing their growth. This medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of your doctor.
How long do you run Meropenem?
Dose to be administered every 8 hours Meropenem is usually given by intravenous infusion over approximately 15 to 30 minutes (see section 6.2, 6.3 and 6.6). Alternatively, doses up to 1 g can be given as an intravenous bolus injection over approximately 5 minutes.
How strong is meropenem?
Typical dosing for meropenem (Merrem) The maximum strength given per dose is 500 mg. Abdominal infections: The dose is 20 mg/kg infused through an IV every 8 hours. The maximum strength given per dose is 1,000 mg.