What happens if I take too much bupropion?
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What happens if I take too much bupropion?
After an overdose of bupropion, clinical effects are primarily on the neurological, cardiovascular and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucination, coma, and seizures. Cardiovascular effects involve tachycardia and conduction defects.
How much bupropion XL is too much?
Adults—At first, 100 milligrams (mg) two times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg three times per day, taken at least 6 hours apart. Children—Use and dose must be determined by your doctor.
Can Wellbutrin be lethal?
Conclusions: Bupropion overdose may lead to recurrent seizures, hypoxia and death. Aggressive management of severe bupropion overdose is recommended.
What happens if you take 300 mg of bupropion?
Dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, or shaking (tremor) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Is 600 mg of Wellbutrin XL too much?
The maximum daily dose of bupropion is 450 mg, but reported cases of abuse have involved ingesting from 600 mg 8 to 1200 mg of the drug 2. Most bupropion abusers take this drug by crushing and snorting (insufflating) the pills.
Is 600 mg of Wellbutrin too much?
How much bupropion is lethal?
Toxic Dose Seizures are most common with doses > 2.5 g. Serious toxicity can be expected with doses > 6 g, and fatalities usually involve doses > 9 g.
What does bupropion do to the brain?
This medication works by improving your mood and your sense of well-being. This is achieved by restoring the chemical balance of dopamine and norepinephrine in the brain. Bupropion is also used off-label for the treatment of a variety of health conditions such as: Attention Deficit Hyperactivity Disorder (ADHD)
What happens if I double my Wellbutrin?
DO NOT take 2 doses at once. You should not take more than your prescribed dose and doing so may increase your risk of having a seizure. For bupropion XL, do not take an extra tablet to make up for the dose you forgot.
How likely is it to have a seizure on Wellbutrin?
Seizures: Bupropion is associated with seizures in approximately 0.4% (4/1,000) of patients treated at doses up to 450 mg/day. This incidence of seizures may exceed that of other marketed antidepressants by as much as 4-fold.